What is polymyxin b sulfate and trimethoprim ophthalmic solution for

Use Polymyxin B And Trimethoprim Ophthalmic (Polytrim) exactly as directed on the label, or as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended.

This medicine is usually applied once every 3 hours for 7 to 10 days. Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.

Wash your hands before using the eye drops.

To apply the eye drops:

  • Tilt your head back slightly and pull down your lower eyelid to create a small pocket. Hold the dropper above the eye with the tip down. Look up and away from the dropper and squeeze out a drop.
  • Close your eyes for 2 or 3 minutes with your head tipped down, without blinking or squinting. Gently press your finger to the inside corner of the eye for about 1 minute, to keep the liquid from draining into your tear duct.
  • Use only the number of drops your doctor has prescribed. If you use more than one drop, wait about 5 minutes between drops.
  • Wait at least 10 minutes before using any other eye drops your doctor has prescribed.

Do not touch the tip of the eye dropper or place it directly on your eye. A contaminated dropper can infect your eye, which could lead to serious vision problems.

Do not use the eye drops if the liquid has changed colors or has particles in it. Call your pharmacist for new medicine.

Use this medication for the full prescribed length of time. Your symptoms may improve before the infection is completely cleared. Skipping doses may also increase your risk of further infection that is resistant to antibiotics.

Store at room temperature away from moisture, heat, and light. Keep the bottle tightly closed when not in use.

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Polytrim Side Effects Center

What Is Polytrim?

Polytrim (polymyxin B sulfate and trimethoprim ophthalmic solution) is an antibiotic indicated in the treatment of surface bacterial infections of the eye, including acute bacterial conjunctivitis, and blepharoconjunctivitis, caused by susceptible strains of the following microorganisms: Staphylococcus aureus, Staphylococcus epidermidis, Streptococcus pneumoniae, Streptococcus viridans, Haemophilus influenzae and Pseudomonas aeruginosa. Polytrim is available in generic form.

What Are Side Effects of Polytrim?

Common side effects of Polytrim include:

  • eye irritation (redness, burning, stinging, or itching), and
  • hypersensitivity reactions (eyelid swelling, itching, increased redness, tearing, or rash)

Dosage for Polytrim

In mild to moderate infections, instill a dose of one drop of Polytrim in the affected eye(s) every three hours (maximum of 6 doses per day) for a period of 7 to 10 days.

What Drugs, Substances, or Supplements Interact with Polytrim?

Polytrim may interact with other drugs. Tell your doctor all medications and supplements you use.

Polytrim During Pregnancy or Breastfeeding

Tell your doctor if you are pregnant or plan to become pregnant before using Polytrim; it is unknown how it would affect a fetus. It is unknown if Polytrim passes into breast milk. Consult your doctor before breastfeeding.

Additional Information

Our Polytrim (polymyxin B sulfate and trimethoprim ophthalmic solution) Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What is polymyxin b sulfate and trimethoprim ophthalmic solution for

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Pink Eye (Conjunctivitis) Symptoms, Causes, Treatments See Slideshow

Polytrim Consumer Information

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Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Stop using this medicine and call your doctor at once if you have:

  • eye pain, swelling, redness, or severe discomfort;
  • crusting or drainage (may be signs of infection);
  • swelling or redness of your eyelids; or
  • new or worsening symptoms.

Common side effects may include:

  • mild burning, stinging, or itching of your eyes.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Read the entire detailed patient monograph for Polytrim (Polymyxin B Sulfate and Trimethoprim Ophthalmic Solution, USP, Sterile)

What is polymyxin b sulfate and trimethoprim ophthalmic solution for

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Polytrim Professional Information

SIDE EFFECTS

The most frequent adverse reaction to POLYTRIM® Ophthalmic Solution is local irritation consisting of increased redness, burning, stinging, and/or itching. This may occur on instillation, within 48 hours, or at any time with extended use. There are also multiple reports of hypersensitivity reactions consisting of lid edema, itching, increased redness, tearing, and/or circumocular rash. Photosensitivity has been reported in patients taking oral trimethoprim.

Read the entire FDA prescribing information for Polytrim (Polymyxin B Sulfate and Trimethoprim Ophthalmic Solution, USP, Sterile)

© Polytrim Patient Information is supplied by Cerner Multum, Inc. and Polytrim Consumer information is supplied by First Databank, Inc., used under license and subject to their respective copyrights.

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Is polymyxin B sulfate and trimethoprim used for pink eye?

Polymyxin B and trimethoprim ophthalmic combination is used to treat bacterial infections of the eye including conjunctivitis (pinkeye; infection of the membrane that covers the outside of the eyeball and the inside of the eyelid) or blepharoconjunctivitis (infection of the membrane that covers the outside of the ...

What are the side effects of polymyxin eye drops?

Common side effects may include: mild burning, stinging, or itching of your eyes..
eye pain, swelling, redness, or severe discomfort;.
crusting or drainage (may be signs of infection);.
swelling or redness of your eyelids; or..
new or worsening symptoms..

What bacteria does polymyxin B treat?

Polymyxin B has rapid in vitro bactericidal activity against major MDR Gram-negative bacteria, such as Pseudomonas aeruginosa, Acinetobacter baumannii and Klebsiella pneumoniae.

Is polymyxin B sulfate and trimethoprim a steroid?

Polytrim (polymyxin B / trimethoprim) does not contain any steroids. There are a few eye medications that combine a steroid with antibiotic(s), such as Maxitrol (neomycin / polymyxin B / dexamethasone) and TobraDex (tobramycin / dexamethasone).