Neomycin polymyxin b sulfates and dexamethasone ophthalmic suspension for ears

Maxitrol Side Effects Center

What Is Maxitrol?

Maxitrol (neomycin and polymyxin B sulfates and dexamethasone) Ophthalmic Suspension Sterile is a combination of two antibiotics and a steroid used to treat bacterial infections of the eyes. Maxitrol is available in generic form.

What Are Side Effects of Maxitrol?

Common side effects of Maxitrol include:

• stinging/burning of the eyes for 1 to 2 minutes when Maxitrol is applied,
• irritation,
• itching,
• redness,
• blurred vision,
• eyelid itching,
• eyelid swelling, or
• sensitivity to light.

Serious side effects are generally not expected with Maxitrol. Use of Maxitrol for prolonged or repeated periods may result in a new fungal eye infection and may increase your risk for other eye problems (e.g., glaucoma, cataracts, delayed wound healing). Do not use Maxitrol for longer than prescribed. Tell your doctor if you experience unlikely but serious side effects of Maxitrol including new or worsening eye symptoms (e.g., discharge, swelling, redness), vision problems, or eye pain.

Seek medical care or call 911 at once if you have the following serious side effects:

• Serious eye symptoms such as sudden vision loss, blurred vision, tunnel vision, eye pain or swelling, or seeing halos around lights;
• Serious heart symptoms such as fast, irregular, or pounding heartbeats; fluttering in your chest; shortness of breath; and sudden dizziness, lightheartedness, or passing out;
• Severe headache, confusion, slurred speech, arm or leg weakness, trouble walking, loss of coordination, feeling unsteady, very stiff muscles, high fever, profuse sweating, or tremors.

This document does not contain all possible side effects and others may occur. Check with your physician for additional information about side effects.

Dosage for Maxitrol

Dosing of Maxitrol: One to two drops in the conjunctival sac(s). In severe disease, drops may be used hourly, being tapered to discontinuation as the inflammation subsides. In mild disease, drops may be used up to four to six times daily.

What Drugs, Substances, or Supplements Interact with Maxitrol?

Avoid other eye medications unless approved by your doctor. Before using Maxitrol, tell your doctor if you are taking an oral steroid medication such as prednisone (Deltasone, Orasone, others). Other drugs may also interact with Maxitrol.

Maxitrol During Pregnancy or Breastfeeding

Talk to your doctor before taking any prescription or over-the-counter medicines. During pregnancy, Maxitrol should be used only when prescribed. It is not known if this drug passes into breast milk. Consult your doctor before breastfeeding.

Additional Information

Our Maxitrol (neomycin and polymyxin B sulfates and dexamethasone) Ophthalmic Suspension Sterile Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

SLIDESHOW

Maxitrol Consumer Information

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have:

• blurred vision, tunnel vision, eye pain, or seeing halos around lights;
• swelling, redness, severe discomfort, crusting or drainage (may be signs of infection);
• pain behind your eyes, sudden vision changes; or
• a wound that will not heal.

Common side effects may include:

• blurred vision; or
• mild eye irritation.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Read the entire detailed patient monograph for Maxitrol (Neomycin, Polymyxin B and Dexamethasone Ophthalmic)

QUESTION

Maxitrol Professional Information

SIDE EFFECTS

Adverse reactions have occurred with corticosteroid/anti-infective combination drugs which can be attributed to the corticosteroid component, the anti-infective component, or the combination. Exact incidence figures are not available since no denominator of treated patients is available.

Reactions occurring most often from the presence of the anti-infective ingredient are allergic sensitizations. The reactions due to the corticosteroid component are: elevation of IOP with possible development of glaucoma, and infrequent optic nerve damage; posterior subcapsular cataract formation; and delayed wound healing. Corticosteroid-containing preparations have also been reported to cause perforation of the globe. Keratitis, conjunctivitis, corneal ulcers, and conjunctival hyperemia have occasionally been reported following use of steroids.

Additional adverse reactions identified from post marketing use include ulcerative keratitis, headache, and Stevens-Johnson syndrome.

The following additional adverse reactions have been reported with dexamethasone use: Cushing's syndrome and adrenal suppression may occur after use of dexamethasone in excess of the listed dosing instructions in predisposed patients, including children and patients treated with CYP3A4 inhibitors.

DRUG INTERACTIONS

No Information provided

Read the entire FDA prescribing information for Maxitrol (Neomycin, Polymyxin B and Dexamethasone Ophthalmic)

© Maxitrol Patient Information is supplied by Cerner Multum, Inc. and Maxitrol Consumer information is supplied by First Databank, Inc., used under license and subject to their respective copyrights.