Long term side effects of cortisone injections

Steroid injections, also called corticosteroid injections, are anti-inflammatory medicines used to treat a range of conditions.

They can be used to treat problems such as joint pain, arthritis, sciatica and inflammatory bowel disease.

Steroid injections are only given by healthcare professionals. Common examples include hydrocortisone, triamcinolone and methylprednisolone.

How steroid injections are given

Steroid injections are usually given by a specialist doctor in hospital.

They can be given in several different ways, including:

  • into a joint (an intra-articular injection)
  • into a muscle (an intramuscular injection)
  • into the spine (an epidural injection)
  • into the blood (an intravenous injection)

The injections normally take a few days to start working, although some work in a few hours. The effect usually wears off after a few months.

If you're having an injection to relieve pain, it may also contain local anaesthetic. This provides immediate pain relief that lasts a few hours.

You should be able to go home soon after the injection. You may need to rest the treated body part for a few days.

Side effects of steroid injections

Possible side effects of steroid injections depend on where the injection is given.

Side effects of injections into the joints, muscles or spine can include:

  • pain and discomfort for a few days – paracetamol may help with this
  • temporary bruising or a collection of blood under the skin
  • flushing of the face for a few hours
  • an infection, causing redness, swelling and pain – get medical advice as soon as possible if you have these symptoms
  • a loss of fat where the injection was given – this can cause dimples in the skin and may be permanent
  • paler skin around the site of the injection – this may be permanent
  • if you have diabetes, your blood sugar level may go up for a few days
  • if you have high blood pressure, your blood pressure may go up for a few days

Epidural injections can also occasionally give you a very painful headache that's only relieved by lying down. This should get better on its own, but tell your specialist if you get it.

Side effects of injections given into the blood tend to be similar to side effects of steroid tablets, such as increased appetite, mood changes and difficulty sleeping.

You can report any suspected side effect to a UK safety scheme.

Who can have steroid injections

Most people can have steroid injections.

Tell the doctor before having treatment if you:

  • have had a steroid injection in the last few weeks – you usually need to wait at least 6 weeks between injections
  • you've had 3 steroid injections in the last year – doctors usually recommend no more than 3 injections in the same area in the space of 12 months
  • have had an allergic reaction to steroids in the past
  • have an infection (including eye infections)
  • have recently had, or are about to have, any vaccinations
  • are pregnant, breastfeeding or trying for a baby
  • have any other conditions, such as diabetes, epilepsy, high blood pressure, or problems with your liver, heart or kidneys
  • are taking other medicines, such as anticoagulants

Steroid injections may not always be suitable in these cases, although the doctor may recommend them if they think the benefits outweigh any risks.

How steroid injections work

Steroids are a manmade version of hormones normally produced by the adrenal glands, 2 small glands found above the kidneys.

When injected into a joint or muscle, steroids reduce redness and swelling (inflammation) in the nearby area. This can help relieve pain and stiffness.

When injected into the blood, they can reduce inflammation throughout the body, as well as reduce the activity of the immune system, the body's natural defence against illness and infection.

This can help treat autoimmune conditions, such as multiple sclerosis (MS), which are caused by the immune system mistakenly attacking the body.

Steroid injections are different from the anabolic steroids used illegally by some people to increase their muscle mass.

Page last reviewed: 26 February 2020
Next review due: 26 February 2023

Cortisone is medicine sometimes injected into the body to help ease pain and swelling from arthritis, injury or illness. Cortisone shots are sometimes called corticosteroid shots.

  • Overview
  • Procedure Details
  • Risks / Benefits
  • Recovery and Outlook
  • When to Call the Doctor
Cortisone Shots
  • Overview
  • Procedure Details
  • Risks / Benefits
  • Recovery and Outlook
  • When to Call the Doctor
  • Back To Top

Overview

What are cortisone shots?

Cortisone shots are injections of medicine that ease pain and swelling in different parts of the body. Doctors use these shots to treat injuries and conditions such as arthritis or autoimmune disorders (when the body’s immune system harms its own cells).

Cortisone is a type of medication called a corticosteroid. Doctors use these drugs to treat inflammation (swelling) caused by injury and illness. Sometimes cortisone shots are called corticosteroid shots. Commonly used cortisone variants include Kenalog® (tramcinolone) Depo-Medrol® (methylprednisolone), and Celestone® (Betamethasone).

People most commonly receive cortisone shots in joints including the hip, knee, shoulder, spine, hands and feet. The cortisone reduces inflammation (swelling) in and around the joint.

Procedure Details

How do cortisone shots work?

Doctors give cortisone shots during an office visit directly into the area or joint involved, or sometimes just into a large muscle to get it into the bloodstream. In other parts of the body, the injection often includes a local anesthetic (pain reliever) to start easing pain immediately. In these cases, cortisone is typically injected into three areas:

  • Joints
  • Tendons
  • Bursa (fluid-filled sacs that act as cushions between joints, tendons, and bones)

Risks / Benefits

What are complications or side effects of cortisone shots?

Cortisone can weaken the immune system. For this reason, many doctors limit injections to once every 3 months for a specific joint, and 6 times a year for the entire body.

Cortisone can also raise blood sugar levels in people with diabetes. Doctors monitor blood sugar levels to make sure they are stable before delivering a cortisone injection. Cortisone may also (more rarely) cause osteoporosis (low bone density), fluid retention (swelling of the limbs and congestion in the lungs), high blood pressure, and alterations in mood.

Patients who take other corticosteroid medication such as prednisone pills or inhaled steroids should get fewer injections or lower doses if possible to minimize the above risks.

All injections have a risk of infection. For this reason, it is important to keep the injection site clean.

Recovery and Outlook

What is the outlook for people after cortisone shots?

It can take up to 7 days for a cortisone injection to begin working in the body. The effects of the injection usually last up to 2 months, but sometimes longer.

Cortisone can reduce inflammation that damages joints. Your doctor also may recommend other treatments to address joint pain resulting from another condition such as obesity, tendon or ligament damage, or an autoimmune disorder.

When to Call the Doctor

When should I call the doctor after a cortisone shot?

Call your doctor if you experience a fever or severe pain, swelling or redness after a cortisone injection. These may be signs of an infection that your doctor can treat with medication.

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Long term side effects of cortisone injections

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Long term side effects of cortisone injections

Can cortisone shots cause long

There's concern that repeated cortisone shots might damage the cartilage within a joint. So doctors typically limit the number of cortisone shots into a joint. In general, you shouldn't get cortisone injections more often than every six weeks and usually not more than three or four times a year.

What is the downside to a cortisone shot?

The Downsides According to the National Institutes of Health, the side effects from cortisone shots include: Dizziness or headaches. Skin issues, including dryness, thinness, acne, dry skin, and red or purple blotches. Fatigue and trouble sleeping.

What are the long

Thinning bones (osteoporosis) and fractures. Suppressed adrenal gland hormone production that may result in a variety of signs and symptoms, including severe fatigue, loss of appetite, nausea and muscle weakness. Thin skin, bruising and slower wound healing.

Does a cortisone shot affect the whole body?

Cortisone can travel into your bloodstream and cause full-body side effects. According to a 2019 review of studies , the amount of cortisone that gets absorbed into your blood seems to vary significantly between people. But both joint and epidural injections can have effects that last for weeks.