Do not use this medicine if you have used an MAO inhibitor in the past 14 days, such as isocarboxazid, linezolid, methylene blue injection, phenelzine, rasagiline, selegiline, or tranylcypromine.
Chlorpheniramine is an antihistamine. Dextromethorphan is a cough suppressant. Phenylephrine is a decongestant.
Chlorpheniramine, dextromethorphan, and phenylephrine is a combination medicine used to treat cough, runny or stuffy nose, sneezing, itching, and watery eyes caused by allergies, the common cold, or the flu.
This medicine will not treat a cough that is caused by smoking, asthma, or emphysema.
Chlorpheniramine, dextromethorphan, and phenylephrine may also be used for purposes not listed in this medication guide.
Ask a doctor or pharmacist if this medicine is safe to use if you have:
- asthma or COPD, cough with mucus;
- a blockage in your digestive tract (stomach or intestines);
- high blood pressure, heart disease;
- liver or kidney disease;
- glaucoma;
- enlarged prostate or urination problems;
- overactive thyroid; or
- pheochromocytoma (an adrenal gland tumor).
Do not use chlorpheniramine, dextromethorphan, and phenylephrine if you have used an MAO inhibitor in the past 14 days. A dangerous drug interaction could occur. MAO inhibitors include isocarboxazid, linezolid, methylene blue injection, phenelzine, rasagiline, selegiline, tranylcypromine, and others.
Ask a doctor before using this medicine if you are pregnant or breastfeeding.
Use exactly as directed on the label, or as prescribed by your doctor. Cold or cough medicine is only for short-term use until your symptoms clear up.
Always follow directions on the medicine label about giving cough or cold medicine to a child. Do not use the medicine only to make a child sleepy. Death can occur from the misuse of cough or cold medicines in very young children.
Measure liquid medicine carefully. Use the dosing syringe provided, or use a medicine dose-measuring device (not a kitchen spoon).
Dissolve the effervescent tablets in at least 4 ounces of water. Stir and drink this mixture right away. Add a little more water to the glass, swirl gently and drink right away.
Do not take for longer than 7 days in a row. Call your doctor if your symptoms do not improve after 7 days, or if you have a fever, rash, or headaches.
If you need surgery or medical tests, tell the surgeon or doctor ahead of time if you have taken this medicine within the past few days.
Store at room temperature away from moisture and heat.
Since this medicine is used when needed, you may not be on a dosing schedule. Skip any missed dose if it's almost time for your next dose. Do not use two doses at one time.
Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.
Drinking alcohol with this medicine can cause side effects.
Avoid driving or hazardous activity until you know how this medicine will affect you. Your reactions could be impaired.
Ask a doctor or pharmacist before using other cough or cold medicines that may contain similar ingredients.
Avoid becoming overheated or dehydrated during exercise and in hot weather. This medicine can decrease sweating and you may be more prone to heat stroke.
Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Stop using this medicine and call your doctor at once if you have:
- severe anxiety, tremor, seizure (convulsions);
- fast or pounding heartbeats;
- painful or difficult urination;
- pale skin, weakness; or
- severe headache, pounding in your neck or ears.
Common side effects may include:
- dizziness, drowsiness;
- blurred vision;
- dry mouth, nose, or throat;
- increased or decreased urination;
- nausea, loss of appetite, diarrhea;
- sleep problems (insomnia); or
- nervousness.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Avoid using this medicine with other drugs that cause drowsiness or slow your breathing (such as opioid medicine, a muscle relaxer, or medicine for anxiety or seizures). Ask a doctor or pharmacist before using any other medication, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed in this medication guide.
Your pharmacist can provide more information about chlorpheniramine, dextromethorphan, and phenylephrine.
Drug Details [pdf]
- SPL UNCLASSIFIED SECTION
- ACTIVE INGREDIENT
- Uses
temporarily relieves these symptoms due to the common cold, hay fever (allergic rhinitis) or other respiratory allergies:
- runny nose
- sneezing
- itching of the nose or throat
- itchy, watery eyes
- cough due to minor throat and bronchial irritation
- nasal congestion
- reduces swelling of nasal passages
- Warnings
Do not exceed recommended dosage.
Do not use this product
- if you are now taking a prescription monoamine oxidase inhibitor (MAOI) (certain drugs for depression, psychiatric, or emotional conditions, or Parkinson's disease), or for 2 weeks after stopping the MAOI drug. If you do not know if your prescription drug contains an MAOI, ask a doctor or pharmacist before taking this product.
Do not use this product, unless directed by a doctor, if you have
- a breathing problem such as emphysema or chronic bronchitis
- glaucoma
- a persistent or chronic cough that occurs with too much phlegm (mucus)
- heart disease
- high blood pressure
- thyroid disease
- diabetes mellitus
- difficulty in urination due to enlargement of the prostate gland
Do not take this product if you are taking sedatives or tranquilizers, without first consulting your doctor.
When using this product
- excitability may occur, especially in children
- may cause marked drowsiness
- sedatives and tranquilizers may increase drowsiness effect
- avoid alcoholic beverages
- use caution when driving a motor vehicle or operating machinery
Stop use and ask doctor if
- nervousness, dizziness, or sleeplessness occur
- cough or nasal congestion persists for more than 1 week, tends to recur, or is accompanied by a fever, rash or persistent headache. These could be signs of a serious condition.
- new symptoms occur
If pregnant or breastfeeding, ask a health professional before use.
Keep out of reach of children.
In case of accidental overdose, seek professional help or contact a Poison Control Center immediately.
- Directions
Do not exceed recommended dosage
- Other information
Store at 59° - 86° F (15° - 30° C) [see USP for Controlled Room Temperature].
- Inactive ingredients
Banana Flavor, Citric Acid, FD&C Blue #1, FD&C Yellow #6, Methyl Paraben, Potassium Citrate, Potassium Sorbate, Propyl Paraben, Propylene Glycol, Purified Water, Sorbitol Solution 70%, Sucralose.
- Question? Comments?
- PRINCIPAL DISPLAY PANEL - 473 mL Bottle Label
E
NDC: 0485-0171-16
ED A-HIST DM
Antihistamine Antitussive
Nasal DecongestantSugar Free Gluten Free
Each teaspoonful (5 mL)
for oral administration contains:
Chlorpheniramine Maleate 4 mg
Dextromethorphan HBr 15 mg
Phenylephrine HCl 10 mgBanana Flavor
Tamper evident by foil seal under cap.
Do not use if foil seal is broken or
missing.Manufactured for:
EDWARDS
Pharmaceuticals, Inc.
Ripley, MS 3866316oz. (473 mL)
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